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Founded in 1947, Dana-Farber Cancer Institute is committed to providing expert, compassionate care to children and adults with cancer, while advancing the understanding, treatment, cure, and prevention of cancer and related diseases. As an affiliate of Harvard Medical School and a Comprehensive Cancer Center designated by the National Cancer Institute, the Institute also provides training for new generations of physicians and scientists, designs programs that promote public health particularly among high-risk and underserved populations and disseminates innovative patient therapies and scientific discoveries in Boston, across the United States and throughout the world.

Right now, young trans people, particularly Black and Brown trans youth, are under attack across the country and around the world. The COVID-19 pandemic has exacerbated unsafe conditions for trans youth who are houseless, in foster care, in detention, and in abusive or otherwise unsafe housing situations. We want to show trans young people that they are loved, supported, and have a family of people around the world who care about them and want them to succeed. Anyone can be a Santa, join us! Transness is so beautiful and we are celebrating our magic! Deliver gifts anonymously to trans youth in need, safely.

The mission of Wounded Warrior Project® (WWP) is to honor and empower wounded warriors. The organization's vision is to foster the most successful, well-adjusted generation of injured service members in our nation’s history, by CONNECTING, SERVING, and EMPOWERING the wounded men and women who so bravely volunteered to serve our nation on or after the events of September 11, 2001. They CONNECT warriors, their families, and caregivers to peers, programs, and communities to ensure they have a readily available network of support. SERVE by providing free mental and physical health and wellness programs, career and benefits counseling, and by providing ongoing support for the most severely injured. And EMPOWER warriors to live life on their own terms, mentor fellow veterans and service members, and embody the WWP logo by carrying one another on a path toward recovery. Today, more than 110,000 wounded warriors and 26,000 family support members and caregivers are registered with WWP and have access to free programs and services that CONNECT, SERVE, and EMPOWER.

The Michael J. Fox Foundation is dedicated to finding a cure for Parkinson's disease through an aggressively funded research agenda and to ensuring the development of improved therapies for those living with Parkinson's today. The Foundation's focus is increasingly on clinical and translational research, crucial to making strides toward a cure and improved therapies for those living with Parkinson's today.

We grant the wishes of children with life-threatening medical conditions to enrich the human experience with hope, strength and joy. Based in Phoenix, the Make-A-Wish Foundation® is one of the nation's leading charities, serving children in every community in the United States, Puerto Rico and Guam. With the help of generous donors and approximately 25,000 volunteers nationwide, the Make-A-Wish Foundation grants a wish every 38 minutes, on average. Since our inception in 1980, we have granted more than 226,000 wishes. Visit the Make-A-Wish Foundation of America at www.wish.org (http://www.wish.org) and discover how you can share the power of a wish®.

The mission of the American Diabetes Association (the Association) is to prevent and cure diabetes and to improve the lives of all people affected by diabetes. Diabetes is a disease in which the body does not produce or properly use insulin.  Insulin is a hormone that is needed to convert sugar, starches and other food into energy needed for daily life.  The cause of diabetes continues to elude the medical community, although research has shown that both genetics and environmental factors such as obesity and lack of exercise appear to play roles.

The American Foundation for Suicide Prevention is dedicated to saving lives and bringing hope to those affected by suicide. AFSP creates a culture that’s smart about mental health through education and community programs, develops suicide prevention through research and advocacy, and provides support for those affected by suicide. AFSP has local chapters in all 50 states with programs and events nationwide.

Samaritan's Purse is a nondenominational evangelical Christian organization providing spiritual and physical aid to hurting people around the world. Since 1970, Samaritan's Purse has helped meet needs of people who are victims of war, poverty, natural disasters, disease, and famine with the purpose of sharing Gods love through His son, Jesus Christ. The organization serves the church worldwide to promote the Gospel of the Lord Jesus Christ.

For over 30 years, Best Friends Animal Society has been running the nation’s largest no-kill sanctuary for companion animals and building effective programs that reduce the number of animals entering shelters. The mission of Best Friends Animal Society is to bring about a time when there are No More Homeless Pets. The organization does this by helping end the killing in America's animal shelters through building community programs and partnerships all across the United States.

The National Multiple Sclerosis Society's mission is to cure multiple sclerosis while empowering people affected by multiple sclerosis (MS) to live their best lives. The organization pledges to accelerate cures through global leadership, and improve access to personalized, affordable, high-quality MS healthcare. It empowers people affected by MS to solve everyday challenges and strengthens the MS movement through more and deeper connections.

Millions of children are on the frontlines of conflict, their lives and futures at grave risk. Without immediate support, the world’s most vulnerable children are at risk of physical and emotional harm with devastating, lifelong consequences. That’s why Save the Children works in the hardest-to-reach places, where it’s toughest to be a child. But we need your help. Together, we can fight threats to children's lives. $50 can provide 10 warm, cozy blankets to children affected by conflict $100 helps supply a month’s worth of nutritious food to a family in crisis $200 could help provide psychosocial support to 20 children With your support, Save the Children is there before, during and after an emergency. Working together, we help communities become more resilient so that each time a crisis happens they are stronger, more likely to survive and able to recover more quickly. Your support today helps make this possible.

To eliminate Alzheimer's disease through the advancement of research; to provide and enhance care and support for all affected; and to reduce the risk of dementia through the promotion of brain health. The Alzheimer's Association is the world's leading voluntary health organization in Alzheimer's care, support and research. We value inclusivity, community, accountability, agility, and integrity. Our commitment to transparency, research, and diversity and inclusion helps to fulfill our vision: a world without Alzheimer's and all other dementia. In 2021, the Alzheimer's Association invested over $70 million in research, launched two new campaigns "Any Given Moment" and "More Time", and strengthened partnerships with faith-based communities. The Alzheimer's Association's powerful advocacy witnessed the Improving HOPE for Alzheimer's Act signed into law through the Association's leadership. At the beginning of the COVID-19 Pandemic, the Association's Walk to End Alzheimer's participants walked in small groups in their neighborhoods to raise $86 million.