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The Trevor Project is the world’s largest suicide prevention and crisis intervention organization for LGBTQ+ (lesbian, gay, bisexual, transgender, queer, and questioning) young people. The organization works to save young lives by providing support through free and confidential suicide prevention and crisis intervention programs on platforms where young people spend their time: a 24/7 phone lifeline, chat, and text. The organization also runs TrevorSpace, the world’s largest safe space social networking site for LGBTQ youth, and operates innovative education, research, and advocacy programs.

Nurse Heroes seeks to provide every nurse with the resources and opportunities they need and create a future without a shortage of nurses. As an accelerating shortage of nurses around the world exists, if nothing changes within three years we will have about 1 million fewer nurses than we require in the United States and a shortage of 2 million nurses in Europe. It is a similar trend globally. The organization is committed to informing and inspiring the world to help create a future without a shortage of nurses and nurse practitioners, celebrating nurses through the arts with celebrity concert series, monthly art contests, and nurse choir performances.

Dedicated to exonerating innocent people through DNA testing and reforming the criminal justice system to prevent wrongful convictions. The Innocent Project works to exonerate the innocent who have been wrongfully convicted, improve case law through targeted legal work, reform to prevent wrongful conviction, support exonerees as they rebuild their lives post-release, research and educate on legal and policy work, and build through alliances with other organizations.

We are a nonprofit agency that promotes justice by providing free and low-cost legal services to under served immigrant children, families, and refugees. With legal services, social programs, bond assistance, and an advocacy team focused on changing the narrative around immigration in this country, RAICES is operating on the national front lines of the fight for immigration rights. We defend the rights of immigrants and refugees, empower individuals, families, and communities, and advocate for liberty and justice. Since 2018, our Bond Fund is the largest in the nation with just under $12 million spent to secure the release of more than 1,200 individuals from ICE detention. Our San Antonio Bus Station Project helped more than 9,000 adults and 12,000 children released from detention understand their legal rights. We have a volunteer program with over 5,000 trained volunteers and pro bono lawyers to perform essential tasks such as accompanying people to ICE check-ins and preparing detained clients for credible fear interviews.

The Southern Poverty Law Center (SPLC) is dedicated to fighting hate and bigotry and to seeking justice for the most vulnerable members of our society. Using litigation, education, and other forms of advocacy, the SPLC works toward the day when the ideals of equal justice and equal opportunity will be a reality. SPLC fights hate by monitoring hate groups and other extremists throughout the United States, exposing their activities to the public, the media and law enforcement. We work with educators, schools, students, and communities through our Learning for Justice initiative to reach our goal of justice for all. Our Civil Rights Memorial Center in Montgomery, Alabama to honor the martyrs of the civil rights movement and to inspire visitors to continue to march for racial equity and social justice.

Thirst Project is a nonprofit organization that works with the support of young people to END the global water crisis by building freshwater wells in developing communities that need safe, clean drinking water, vital to health and sanitation. The Thirst Project seeks to provide health and sanitation. As waterborne diseases kill more children every single year than HIV, Malaria, and all world violence combined. And small children are at significant risk, as they typically do not have strong enough immune systems to fight diseases like cholera, dysentery, or schistosomiasis. By providing a community with safe drinking water, disease rates can drop by up to 88% virtually overnight! Child mortality rates can drop up to 90%- overnight! Likewise, the time children spend collecting water keeps them from going to school and getting an education. Women and children spend on average six to eight hours each day walking to fetch water. The average distance that women and children in developing communities walk to fetch water is 3.75 miles. The Thirst Project makes clean water accessible, lowers health risks and empowers children's education.

For over 30 years, Best Friends Animal Society has been running the nation’s largest no-kill sanctuary for companion animals and building effective programs that reduce the number of animals entering shelters. The mission of Best Friends Animal Society is to bring about a time when there are No More Homeless Pets. The organization does this by helping end the killing in America's animal shelters through building community programs and partnerships all across the United States.

Provide Clean Water: In the past this fund has supported education and empowerment surrounding clean water initiatives, as well as implementation of clean water projects through nonprofits like the Thirst Project.

Drive local action for global ocean conservation.

Autism Speaks is dedicated to promoting solutions, across the spectrum and throughout the life span, for the needs of individuals with autism and their families. We do this through advocacy and support; increasing understanding and acceptance of people with autism; and advancing research into causes and better interventions for autism spectrum disorder and related conditions. ​Through partnerships and collaboration, we are committed to: ​​Increasing global understanding & acceptance of people with autism Being a catalyst for life-enhancing research breakthroughs Increasing early childhood screening & timely interventions Improving the transition to adulthood Ensuring access to reliable information & services throughout the life span.

The Breast Cancer Research Foundation (BCRF) is dedicated to being the end of breast cancer by advancing the world's most promising research. Founded by Evelyn H. Lauder in 1993, BCRF-funded investigators have been deeply involved in every major breakthrough in breast cancer prevention, diagnosis, treatment and survivorship. This year, BCRF has awarded $63 million in grants to support the work of nearly 300 scientists at leading medical and academic institutions across 14 countries, making BCRF the largest private funder of breast cancer research worldwide. BCRF is also the highest rated breast cancer organization in the U.S. Visit www.bcrf.org to learn more.

The mission of Doctors Without Borders/Médecins Sans Frontières (MSF) is to provide impartial medical relief to the victims of war, disease, and natural or man-made disaster, without regard to race, religion, or political affiliation. A non-profit, self-governed, member-based organisation, MSF's global reach is demonstrated by a presence in over 72 countries and territories with medical humanitarian projects, 9,904,200 medical consultations conducted by humanitarian teams, and 877,300 patients admitted to MSF hospitals or clinics around the world.